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Idiopathic giant-cell myocarditis
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Idiopathic giant-cell myocarditis : ウィキペディア英語版
Idiopathic giant-cell myocarditis

Idiopathic giant-cell myocarditis (IGCM) is a cardiovascular disease.
The condition is rare; however, it is often fatal and there is no proven cure because of the unknown nature of the disorder.
IGCM frequently leads to death with a high rate of about 70% in first year. A patient with IGCM typically presents with symptoms of heart failure although some may present initially with ventricular arrhythmia or heart block. Median age from the time the disease is diagnosed to the time of death is approximately 6 months. 90% of patients are either deceased by the end of 1 year or have received a heart transplant. Diagnosis is made by endomyocardial biopsy during heart catheterization. Biopsy shows multinucleated giant cells and thus the name. There is no treatment except for heart transplantation. The transplanted heart has a high chance of disease recurrence. Compared to lymphocytic (presumed viral) myocarditis, giant cell myocarditis is much more severe with much more rapid progression.
It is suggested to be caused by T-lymphocytes.
==See also==

* Idiopathic
* Giant cell
* Myocarditis

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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